It comes as no secret that the term 'tranny' doesn't sit well with me, having a transgender partner and all. Usually the comparison I make to try and get people to understand is that it's like using 'nigger' to refer to a black person or 'faggot' to refer to a gay person. Especially since it has been an acceptable part of our vernacular for years, much like the other two terms were at one time (and in places, still are). For this reason a lot of people don't consider it to be a slur, and considering the history of the other two, that's perfectly understandable.